The State of Wyoming is a state in the western region of the United States of America. The easternmost section of the state is a region known as the High Plains due to its altitude above sea level, while the majority of the state is dominated by the mountain ranges and rangelands of the Rocky Mountain West. Wyoming is the least populous U.S. state. The United States Census Bureau estimates that the state population was 515,004 in 2006, a 4.3% increase since 2000. The capital and the most populous city of Wyoming is Cheyenne. Residents of Wyoming are known as Wyomingites.

The region known today as the state of Wyoming was originally inhabited by several Native American groups. The name Wyoming is derived from the Delaware (Munsee) word meaning "at the big river flat," originally applied to the Wyoming Valley in Pennsylvania. The Crow, Arapaho, Lakota, and Shoshone were but a few of the original inhabitants encountered when white explorers first entered the region. Although French trappers may have ventured into the northern sections of the state in the late 1700s, John Colter, a member of the Lewis and Clark Expedition, was probably the first white American to enter the region in 1807. His reports of the Yellowstone area were considered at the time to be fictional. Robert Stuart and a party of five men returning from Astoria discovered South Pass in 1812. The route was later followed by the Oregon Trail. In 1850, Jim Bridger located what is now known as Bridger Pass, which was later used by both the Union Pacific Railroad in 1868, and in the 20th century by Interstate 80. Bridger also explored the Yellowstone region and like Colter, most of his reports on that region of the state were considered at the time to be tall tales.

After the Union Pacific Railroad reached the town of Cheyenne, which later became the state capital, in 1867, the population began to grow steadily in the Wyoming Territory, which was established on July 25, 1868. Unlike Colorado to the south, Wyoming never experienced a rapid population boom from any major mineral discoveries such as gold or silver. Copper was found in some areas of the state.

Once government sponsored expeditions to the Yellowstone country were undertaken, the previous reports by men like Colter and Bridger were found to be true. This led to the creation of Yellowstone National Park, which became the world's first National Park in 1872. It is located in the far northwestern portion of the state. Most of the territory that comprises Yellowstone National Park is located in Wyoming.

Wyoming was admitted to the Union on July 10, 1890. It was named after the Wyoming Valley of Pennsylvania, made famous by the 1809 poem Gertrude of Wyoming by Thomas Campbell. The name was suggested by Representative J. M. Ashley of Ohio.

In 1869, Wyoming extended much suffrage to women, at least partially in an attempt to garner enough votes to be admitted as a state. In addition to being the first U.S. state to extend suffrage to women, Wyoming was also the home of many other firsts for U.S. women in politics. For the first time, women served on a jury in Wyoming (Laramie in 1870). Wyoming had the first female court bailiff (Mary Atkinson, Laramie, in 1870) and the first female justice of the peace in the country (Esther Hobart Morris, South Pass City, in 1870). In 1924, Wyoming became the first state in the Union to elect a female governor, Nellie Tayloe Ross, who took office the following January.

Wyoming was the location of the Johnson County War of 1892 which was fought between large cattle operators and free ranging interest groups. This war was fought because of the new ranchers moving in following the passage of the homestead act.